Glucosamine - A Review of Literature

A brief technical summery of past publications which substantiated the effects of Glucosamine HCL

Glucosamine FAQs

Get answers for your questions regarding Glucosamine

Glucosamine HCl vs. Sulfate

There is discussion over which of the two glucosamine salts, hydrochloride or sulfate, is preferred for the treatment of osteoarthritis.

Glucosamine Study at Mount Sinai Hospital

A recently completed clinical trial study of glucosamine hydrochloride was completed at Mt. Sinai Hospital in Toronto. Here are the results of this study.

Creatine Strengthens Elderly

Creatine strengthens ill, elderly, study shows.

University of Massachusetts - Creatine Study

Subjects experienced a greater increase in serum creatine concentrations when ingesting CREATEAM Creatine Chewable Tablets compared to powders.

Glucosamine Abstracts Section

There are 20 abstracts of Glucosamine Research below

1. Effect Of Hexosamines On The Synthesis Of Chondroitin Sulphuric Acid In Vitro

Chemisty Dept. II, Karolinska Institutet, Stockholm, Sweden; Arkiv for Kemi Band 10 nr 23 (1956)

2. Effects Of Hexosamine Derivatives And Uronic Acid Derivatives On Glycosaminoglycane Metabolism Of Fibroblast Cultures

K. Karzel and R. Domenjoz, Institute of Pharmacology, University of Bonn; Pharmacology 5: 337-345 (1971)

3. Effects Of D-glucosamine Concentration On The Kinetics Of Mucopolysaccharide Biosynthesis In Cultured Chick Embryo Vertebral Cartilage

Jung Ja Kim and H. Edward Conrad, Department of Biochemistry, University of Illinois, Urbana, IL; The Journal of Biologhical Chemisty, Vol. 249, No. 10, Issue of May 25, pp. 3091-3097 (1974)

4. Articular Cartilage Pharmacology: I. In Vitro Studies On Glucosamine And Non Steroidal Anti-inflammatory Drugs

R. R. Vidal y Plana, D. Bizzarri, A. L. Rovati, Rota Research Laboratories S.p.A., Milan, Italy; Pharmacological Research Communications, Vol. 10, No. 6 (1978)

5. Glucosamine: Its Role In The Articular Cartilage Metabolism; 2. Studies On Rat And Human Articular Cartilage

R. R. viday y Plana (Rota Research Laboratories S.p.A, Milan, Italy) and K. Karzel (Institute of Pharmacology and Toxicology, University of Bonn, Bonn, Germany); Fortschr. Med. 98, 801-806 (1980)

6. The Basic Treatment Of Osteoarthrosis

Jose M. Pujalte, M.D. , Elpidio P. Llavore, M.D. and Florencito R. Ylescupidez, M.D., Nat'l Orthopedic Hospital, Manila, Phillippines; Current Med. Res. and Opinion (1980), 7, 110

7. Glucosamine Sulphate For The Management Of Arthrosis: A Controlled Clinical Investigation

G. Crolle, M.D. and E. D'Este, M.D., Hospital 'G. B. Giustinian', 1st Medical Division, Venice, Italy; Curr. Med. Res. Opin, (1980), 7, 104

8. Therapeutic Activity Of Oral Glucosamine Sulfate In Osteo-arthrosis: A Placebo-controlled Double-blind Investigation

A Drovanti - Vigevano General Hospital, Italy; A. A. Bignamini - Institute of Biological Chemistry, University of Pavia, Italy; A. L. Rovati - Rotta Research Laboratorium, Milano, Italy; Clinical Therapeutics/Vol. 3. No. 4, (1980)

9. Double-blind Clinical Evaluation Of Intra-articular Glucosamine In Outpatients With Gonarthrosis

Yongyudh Vajaradul, Dept. of Orthopedic Surgery, Faculty of Med., Siriraj Hospital, Mahidol University, Bangkok, Thailand; Clinical Therapeutical/vol. 3, No. 5 (1981)

10. Glucosamine Sulphate: A Controlled Clinical Investigation In Arthrosis

E. D'Ambrosia, B. Casa, R. Bompani, G. Scali & M. Scali - Hospital "G Stuard", II Division, Parma, Italy; Pharmatherapeutica, (1981), 2, 504

11. Double-blind Clinical Evaluation Of The Relative Efficacy Of Ibuprofen And Glucosamine Sulphate In The Management Of Osteoarthrosis Of The Knee In Out-patients

Antonio Lopes Vaz, M.D. St. John Hospital, Oporto, Portugal; Current Med. Res. and Opinion, (1982), 8, 145

12. Oral Glucosamine Sulphate In The Management Of Arthrosis: Report On A Multi-center Open Investi-gation In Portugal

Macrio Joao Tapadinhas, Italo Croce Rivera and Angelo A. Bignamini, Orthopedic Service, Principal Military Hospital, Lisbon, Portugal, and Institute of Biological Chemistry, University of Pavia, Pavia, Italy, Pharmatherapeutica (1982), 3, 157

13. Pharmacokinetics of Glucosamine in The Dog and in Man

I. Setnikar, C. Giacchetti, and G. Zanolo - Rotta Research Laboratorium, Monza (Italy) and Instituto di Ricerche Biomediche "Antoine Marxer" S.p.A.; Arzneim.-Forsch./Drug Res. 36(I), Nr. 4 (1986)

14. Anti-reactive Properties of Glucosamine Sulfate

I. Setnikar, R. Cereda, M. A. Pacini, and L. Revel, Rotta Research Laboratories S.p.A., Monza (Italy); Arzneim.-Forsch./Drug Res. 41 (1), Nr. 2(1991)

15. Post-translational Alterations in Newly Synthesized Cartilage Pro-teoglycans Induced by the Glut-amine 6-diazo-5-oxo-l-norleucine

Charles C. Clark, Charlotte F. Richards and Renato V. Iozzo - Depts. of Orthopaedic Surgery, and Biochemistry & Biophysics, Univ. of Pennsyl-vania School of Medicine and Dept. of Pathology and Cell Biology, Thomas Jefferson University; Biochem. J. (1991) 273, 283-288 (Printed in Gr. Britain)

16. Clinical Research in Osteoarthritis: Design and Results of Short-term and Long-term Trials with Disease-Modifying Drugs

L. C. Rovatti, Dept. of Clinical Pharmacology, Rotta Research Laboratorium S.p.A., Monza, Italy; Int. Journal of Tiss. Reac. XIV(5)243-251 (1992)

17. Pharmacokinetics of Glucosamine in Man

I. Setnikar, R. Palumbo, S. Canali, and G. Zanolo - Rotta Research Laboratorium S.p.A, Monza, Policlinico di Perugia, Perugia, and RBM - Instituto di Ricerche Biomediche A. Marxer, Ivera (Italy); Arzneim. Forsch./Drug Res. 43 (II), Nr. 10 (1993)

18. Glucosamine Sulfate in Osteoarthritis of the Knee

Wolfgang Noack, Michael Fischer, Klaus K. Forster, Lucio E. Rovati, and Ivo Setnikar - Dept. of Orthopedics-Evangelisches Waldkrankenhaus (Berlin, Germany); Institute for Numerical Statistics GmbH (Koln, Germany); Dept. of Clinical Research, Opfermann Arzneimittel GmbH (Wiehl, Germany); Dept. of Clinical Pharmacology, Rotta Research Laboratorium (Monza, Italy); Osteoarthritis and Cartilage (1994) 2, 51-59 - Osteoarthritis Research Society

19. Glucosamine Sulfate Compared to Ibuprofen in Osteoarthritis

Hans Muller-Fasbender, Gerhard L. Bach, Wolfgang Haase, Lucio C. Rovati, and Ivo Setnikar, Rheumazentrum, Bad Abbach, Germany; Klinik Herzoghohe, Bayreuth, Germany; Institute for Numerical Statistics GmbH, koln, Germany; Dept. of Clinical Pharmacology, Rotta Research Laboratorium, Monza, Italy; Osteoarthritis and Cartilage (1994) 2, 61-69 - The Osteoarthritis Research Society

20. Efficacy and Safety of Intra-muscular Glucosamine Sulfate In Osteoarthritis Of The Knee - A Randomised, Placebo-controlled, Double-blind Study

A. Reichelt¹, K.K. Forster³, M. Fischer², L.C. Rovati³, and I. Setnikar³- [¹Univ. Clinic of Orthopedics, Freiburg/Brsg. (Fed. Rep. of Germany); ²Institute for Numerical Statistics GmbH, Cologne (Fed. Rep. of Germany); and ³Department of Clinical Pharmacology, Rotta Research Laboratories, Monza, Milan (Italy)]; Arzneim.-Forsch./Drug Res. 44(I), Nr. 1 (1994)